上腹部痛(Epigastric Pain)シリーズ15 EXPERT COURSE 解答 【症例 EE 71】

総胆管結石・肝動脈瘤.CBD stone・hepatic artery aneurysm







胆嚢(GB)がやや腫大し,図10から総胆管(CBD)が拡張しているので尾側へ追跡すると,図18で結石を認め(↑),上腹部痛と黄疸の原因は総胆管結石である.図6〜図12の▲は動脈瘤と思われ,肝門部に位置し肝動脈が接して併走するので肝動脈瘤と診断する.脾臓は最長15cmを超えないがやや腫大しており,図4〜図10の左胃静脈(V)が拡張している原因は図11の△部で動脈瘤が門脈を圧排し,門脈圧亢進症を起こしているためである.図AのERCPで動脈瘤が総胆管を圧排している(△)が肝内胆管の拡張はない.総胆管内に数個の結石を認め(↑),EST・結石除去を行った.図Bの血管造影で右肝動脈起始部で発生した動脈瘤を認め(▲),コイルで塞栓したが,図Cで造影される部分が残存しており(白矢印),さらに追加塞栓を行うか検討中である.















参考症例(腹腔動脈瘤):40歳男性.検診の腹部エコー検査で異常を指摘され発見された腹腔動脈瘤(↑).血管造影で腹腔動脈はSMAから分枝し,起始部に3cm大の動脈瘤を認める(▲).大学病院で手術された.




文献考察1):肝動脈瘤.全腹部内臓動脈瘤306例中肝動脈瘤は36例(12%).有症状のもの,多発性と非動脈硬化例(fibromuscular dysplasia, polyarteritis nodosa, history of endocarditis)が破裂しやすい因子でinterventionの適応である
J Vasc Surg. 2003 Jul;38(1):41-5.
Hepatic artery aneurysm: factors that predict complications.
Abbas MA, Fowl RJ, Stone WM, Panneton JM, Oldenburg WA, Bower TC, Cherry KJ, Gloviczki P.

OBJECTIVE: We reviewed the Mayo Clinic experience with management and outcome of hepatic artery aneurysms (HAA). METHODS: Retrospective review of charts for 306 patients with true visceral aneurysm diagnosed from 1980 to 1998 enabled identification of 36 patients (12%) with HAA. RESULTS: Patients with HAA included 23 men and 13 women, with mean age of 62.2 years (range, 20-85 years). Most aneurysms were extrahepatic (78%) and single (92%). Mean aneurysm diameter at presentation was 3.6 cm (range, 1.5-14 cm). Five aneurysms had ruptured (14%), and four were symptomatic (11%). Mortality from rupture was 40%. Of the 9 patients with ruptured or symptomatic aneurysms, 2 patients had multiple HAA, 3 patients had fibromuscular dysplasia, and 2 patients had polyarteritis nodosa. All five HAAs that ruptured were of nonatherosclerotic origin (P =.001). Fourteen patients (39%) underwent elective procedures, including excision with vein graft (n = 7), excision with dacron graft (n = 3), excision alone (n = 2), and percutaneous embolization (n = 2). Two vein grafts and one dacron graft became occluded within 1 year. Nonoperative management was elected in 22 patients (61%) with mean aneurysm diameter 2.3 cm (range, 1.5-5 cm). No complications related to the aneurysm occurred during mean follow-up of 68.4 months (range, 1-372 months). Aneurysm growth was identified in 27%, the greatest being 0.8 cm over 34 months. CONCLUSIONS: HAA are at definite risk for rupture (14%). Risk factors for rupture include multiple HAA and nonatherosclerotic origin. Patients with symptomatic aneurysms or any of these risk factors should be considered for intervention.PMID: 12844087
本文中のCONCLUSIONS:Although rare, HAA are at definite risk for rupture. Not all HAA need intervention, and small (
文献考察2):腹部内臓動脈瘤破裂.死亡率は25%.腹腔動脈瘤破裂の死亡率は100%に近い
J Vasc Surg. 2001 Apr;33(4):806-11.
Visceral artery aneurysm rupture.
Carr SC, Mahvi DM, Hoch JR, Archer CW, Turnipseed WD.

PURPOSE: Aneurysms of the visceral arteries are infrequently encountered. Many are found incidentally and are thought to have a benign outcome. To better characterize these lesions and their clinical course, we reviewed our experience with visceral artery aneurysms (VAAs) at a single institution. METHODS: A retrospective analysis of all VAAs diagnosed at our institution over the past 10 years was performed. The presentation, management, and outcome of therapy was examined for each patient. RESULTS: Thirty-four VAAs in 26 patients were diagnosed over the past 10 years. Four patients had multiple VAAs: splenic (17), hepatic (7), celiac (3), superior mesenteric (2), gastroduodenal (2), pancreaticoduodenal (1), right gastric (1), ileal (1) artery aneurysms. Associated aneurysms were found in 31% of patients and involved the thoracic aorta (3 patients), abdominal aorta (4 patients), renal arteries (2 patients), iliac artery (3 patients), lower extremity (1 patient), and intracranium (1 patient). In 15 patients (58%), VAAs were detected before rupture by chance or because abdominal symptoms resulted in diagnostic evaluation. Eight of these underwent elective surgery, and there were no deaths. Of those 15 patients with known VAAs, one patient died of rupture and hemorrhage from an untreated splenic artery aneurysm. Eleven patients (42%) presented unexpectedly with rupture, and two died despite prompt surgical treatment. The mortality rate in patients who had ruptured VAAs was 25%, including those who presented with ruptured aneurysms and those observed whose aneurysms eventually ruptured. CONCLUSIONS: Aneurysms of the visceral arteries are rare but important vascular lesions. Associated aneurysms are common. Because of the risk of rupture, often with a fatal outcome, an aggressive approach to the treatment of VAA is essential.PMID: 11296336

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