右下腹部痛(Right Lower Quadrant Pain)シリーズ14 RESIDENT COURSE 解答 【症例 RR 70】

穿孔性虫垂炎.Perforated appendicitis.









図6の1と図5の2の糞石〜図14の12が虫垂である.図4〜図11で広範囲の脂肪組織濃度上昇(phlegmon)を示し(▲),図4〜図15では左側結腸傍腔と骨盤腔内に腹水を認め(白矢印),図1〜図3では左側腹膜の造影・肥厚を呈している(△)ので,限局されない遊離腹腔内への穿孔性虫垂炎である.手術所見:穿孔性虫垂炎(図A,図B:粘膜面).病理:phlegmonous appendicitis with perforation.









文献考察:CTと腹部エコー検査.14の文献の検討から,CTの方が診断の精度が高い
Ann Intern Med. 2004 Oct 5;141(7):537-46.
Systematic review: computed tomography and ultrasonography to detect acute appendicitis in adults and adolescents.
Terasawa T, Blackmore CC, Bent S, Kohlwes RJ.
BACKGROUND: Although clinicians commonly use computed tomography or ultrasonography to diagnose acute appendicitis, the accuracy of these imaging tests remains unclear. PURPOSE: To review the diagnostic accuracy of computed tomography and ultrasonography in adults and adolescents with suspected acute appendicitis. DATA SOURCES: The authors used MEDLINE, EMBASE, bibliographies, review articles, textbooks, and expert opinion to retrieve English- and non-English-language articles published from 1966 to December 2003. STUDY SELECTION: The authors included prospective studies evaluating computed tomography or ultrasonography followed by surgical confirmation or clinical follow-up in patients at least 14 years of age with suspected appendicitis. DATA EXTRACTION: One assessor (for non-English-language studies) or 2 assessors (for English-language studies) independently reviewed each article to abstract relevant study characteristics and results. DATA SYNTHESIS: Twelve computed tomography studies and 14 ultrasonography studies met inclusion criteria. Computed tomography had an overall sensitivity of 0.94 (95% CI, 0.91 to 0.95), a specificity of 0.95 (CI, 0.93 to 0.96), a positive likelihood ratio of 13.3 (CI, 9.9 to 17.9), and a negative likelihood ratio of 0.09 (CI, 0.07 to 0.12). Ultrasonography had an overall sensitivity of 0.86 (CI, 0.83 to 0.88), a specificity of 0.81 (CI, 0.78 to 0.84), a positive likelihood ratio of 5.8 (CI, 3.5 to 9.5), and a negative likelihood ratio of 0.19 (CI, 0.13 to 0.27). Verification bias and inappropriate blinding of reference standards were noted in all of the included studies. LIMITATIONS: The summary assessment of the diagnostic accuracy for both tests was limited by the small number of studies, heterogeneity among study samples, and poor methodologic quality in the original studies. CONCLUSIONS: Computed tomography is probably more accurate than ultrasonography for diagnosing appendicitis in adults and adolescents. Prospective studies that apply gold standard diagnostic testing to all study participants would more reliably estimate the true diagnostic accuracy of these tests.PMID: 15466771(full text)

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