文献考察:膵損傷と血清アミラーゼ値
1)【外傷性膵・十二指腸損傷の診断と治療】 外傷性膵損傷に対する診断と治療(解説/特集)
Author:大森浩明(岩手医科大学 救急医), 旭博史, 井上義博, 藤野靖久, 入野田崇, 遠藤重厚, 斎藤和好
Source:日本腹部救急医学会雑誌(1340-2242)21巻8号 Page1317-1323(2001.11)
追記:膵損傷28例(鋭的外傷1例)中血清アミラーゼ値が異常域例は68%,32%は正常域例であった.
2)Ann Surg. 1997 Jul;226(1):70-6. Serum amylase level on admission in the diagnosis of blunt injury to the pancreas: its significance and limitations.
Takishima T, Sugimoto K, Hirata M, Asari Y, Ohwada T, Kakita A.
OBJECTIVE: The objective of this study was to elucidate the significance and limitations of serum amylase levels in the diagnosis of blunt injury to the pancreas. SUMMARY BACKGROUND DATA: Several recently published reports of analyses of patients with blunt abdominal trauma have indicated that determination of the serum amylase level on admission seemed to be of little value in the diagnosis of acute injury to the pancreas. Few previous reports have described clearly the significance and the limitations of the serum amylase level in diagnosing injury to the pancreas. METHODS: Retrospective analysis of 73 patients with blunt injury to the pancreas during 16-year period from February 1980 to January 1996 was performed. The factors analyzed in the current study included age, gender, time elapsed from injury to admission, hypotension on admission, type of injury to the pancreas, intra-abdominal- and intracranial-associated injuries, and death. RESULTS: The serum amylase level was found to be abnormal in all patients admitted more than 3 hours after trauma. Various comparisons between patients with elevated (n = 61, 83.6%) and nonelevated (n = 12, 16.4%) serum amylase levels showed the statistical significance solely of the time elapsed from injury to admission (7 +/- 1.5 hours vs. 1.3 +/- 0.2 hour, p
追記:膵損傷例で受傷後3時間以内に入院した例で24%に血清アミラーゼ値が正常域で,3時間以上経過して入院した例では全例に血清アミラーゼ値の上昇を認めた.
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