外傷(Trauma)シリーズ2 RESIDENT COURSE 解答 【症例 TR 8】

外傷性肝膿瘍 posttraumatic liver abscess



図1〜図5までの△は被膜下の,図4〜図8の▲は肝実質内のガスと低吸収値の液体でニボーを形成し,不整形で膿瘍であろう.図1〜図7の肝中央部の液貯留(↑)は,図3でdensityは1が42.7 HU,2が38.4 HUと30以上だから血腫,bilio-hematomaまたは感染した血腫で,bilomaは20以下といわれるので単純な bilomaではない.図Aのごとく経皮的経肝的ドレナージで膿が排出され,1ヶ月で治癒退院した.膿培養からはα-streptococcusが検出された.






参考症例(感染性biloma):63歳男性.運転中の交通事故で右胸腹部を打撲し来院した.血圧:170/88mmHg,脈拍:96/分.腹部全体に軽度の圧痛があるが軟.






肝右葉に損傷があり,図2と図3でextravasationと思われる造影剤の貯留(△)を認める.血管造影でextravasation(図6:▲)が確認され塞栓術で止血に成功した.2週間後に38度台の発熱が出現した(下段の図7〜図12).肝損傷部と肝外(図11と図12:※)に低濃度の液貯留を認めるが,図8でガス(↑)を認め,感染を強く示唆する.図9と図10の白矢印は脂肪組織が存在する部位だから,ガスか脂肪組織か判断不可能である.経皮的ドレナージで胆汁が排出され,まもなく解熱した.胆汁の培養でE.coli が検出された.






文献考察:保存的治療後の外傷性肝膿瘍の頻度は1.5%で,すべてAAST grade III以上の症例
Langenbecks Arch Surg. 2003 Jan;387(9-10):343-7.
Liver abscess after non-operative management of blunt liver injury.
Hsieh CH, Chen RJ, Fang JF, Lin BC, Hsu YP, Kao JL, Kao YC, Yu PC, Kang SC, Wang YC.

BACKGROUND: The non-operative management of blunt liver trauma can be applied in almost 80% of patients with this type of injury, with the advantages of the need for fewer blood transfusions, less intra-abdominal sepsis, and a better survival rate, than with the operative approach. However, liver abscess, as a known complication of the non-operative management of blunt liver trauma, is discussed infrequently. Therefore, we herein review our experience and describe this complication in detail. MATERIALS AND METHODS: From 1995 to 2001, 674 patients were admitted to our hospital due to blunt hepatic trauma. Among these patients, 279 underwent laparotomy and the remaining 395 patients were treated non-operatively. Twenty-two patients were identified as having liver abscess, with 16 of them belonging to the operative group, and six to the non-operative group. A retrospective review of these six patients and their characteristics, as well as pathogenesis, diagnosis, and the management of the liver abscesses, was conducted. RESULTS: These six patients were all male, with a median age of 19.5 years (range 3-24). The median injury severity score was 16.5 (range 9-25); three patients sustained grade-3 hepatic injury, and the other three were grade 4. The main diagnostic tool was abdominal computed tomography, and the abscesses took a median of 6 days (range 1-12) to form and be diagnosed. The abscesses were usually caused by infection from mixed organisms, and an abscess resulting from Clostridium infection developed within 1 day after injury. These abscesses were treated with antibiotics and drainage, and the median length of hospital stay was 26 days (range 8-44), without mortality or long-term morbidity. CONCLUSION: Liver abscess as a complication of the non-operative management of blunt hepatic trauma is a rare entity, with an incidence of 1.5% (6/395). It is usually seen in severe liver injury (grade 3 and above), but all our patients were all treated successfully, with no mortality. However, prolonged hospitalization may be required in this patient group. PMID: 12536329

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